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Methylation FFPE analysis

Archival Formalin-Fixed Paraffin-Embedded (FFPE) samples hold an abundance of invaluable information for human cancer studies. Because these samples generally yield highly degraded DNA and RNA, they perform poorly in most whole-genome genotyping and expression studies. This issue has been recently solved for genotyping and expression studies that require the use of microarrays. We have tested these new products and we are now proud and confident to offer genotyping and expression workflows adapted for FFPE samples.

Illumina beadchip

The Infinium MethylationEPIC BeadChip's unique combination of comprehensive, expert-selected coverage, high sample throughput and affordable price make it an ideal solution for methylation analysis in FFPE samples. The array interrogates > 850,000 methylation sites, selected with guidance from a consortium of methylation experts, with single base resolution.